Arizona Sen. John McCain, the war hero who became the GOP's standard-bearer in the 2008 election, has died. He was 81.

His office says McCain died Saturday. He had battled brain cancer.

In 1967, his plane was shot down on a bombing mission over North Vietnam. He was severely injured and spent more than five years as a prisoner of war.

He was elected to the House of Representatives in 1982 and the Senate in 1986. A conservative on most issues, he pushed for campaign finance reform and the effort to account for those missing in Vietnam.

He ran unsuccessfully for the Republican presidential nomination in 2000, then won it in 2008. But he and running mate Sarah Palin lost to Barack Obama.

STATEMENT FROM THE OFFICE OF SENATOR JOHN McCAIN

Washington, D.C. – The office of Senator John McCain released the following statement today:

“Senator John Sidney McCain III died at 4:28pm on August 25, 2018. With the Senator when he passed were his wife Cindy and their family. At his death, he had served the United States of America faithfully for sixty years.”