...Or, in some cases, they probably did.
Clemens Field was home to minor league baseball in 1947 and 1948 in the Central Association and from 1952 through 1955 in the Mississippi-Ohio Valley League.
Both leagues were forerunners the present day Midwest League. Both leagues also operated from time to time in locations later used by the Central Illinois Collegiate League and the Prospect League.  A search through the Baseball-Reference.com website turns up names of several recognizable major leaguers who likely came through Clemens Field on their way to the bigs. This listing doesn’t include everyone who made it into the major leagues, but it does hit the high points…
HANNIBAL  Hannibal Citizens 1955 ,(indep)  Hannibal Cardinals 1953 & 54, Hannibal Stags (indep) 1952,  Hannibal Pilots 1947&48 (STL Browns)
Julio Navarro ’55  Angels ’62-’64 Tigers ’64-’66 Braves ‘70 (signed from Hannibal by NY Giants in July 55) [Father of  former Milwaukee Brewers pitcher Jaime Navarro]
Gary Geiger ’54 (STL) ’58 Cleveland, ’59 thru ’65 Boston, 66-67 Atlanta, 69-70 Houston
John Wyatt ’54 (STL) ’61-66 KC A’s, 66-68 Boston, ’68 Yankees, 68 Detroit, 69 Oakland.
Roy Sievers ’47 (Browns) Browns ’49-’53, Washington ’54-’59, White Sox ’60-’61, Phillies ’62-’64, Washington ’64-’65..
DUBUQUE  1955  Dubuque Packers (White Sox)
Lou Johnson ’55 (PIT)  Cubs ’60 &’68, Angels ’61& ‘69, Braves ’62, Dodgers ’65-67, Indians ‘68
MATTOON 1955 (Phillies)
Dallas Green ’55 (phi) 4-3 record with 55 innings pitched in eight starts for the future Cubs General Manager...
KOKOMO   (Giants)
Orlando Cepeda ’55 Giants  21 HR, .393 in 92 games. A dozen years later, Cepeda helps the Cardinals to back to back World Series appearances...
Walt Dixon (Quincy Cubs manager in late 60’s and in ’73)
DANVILLE 1954 (Giants)
Leon Wagner ’54 Giants ’58 & ’59 & ‘69, Angels ’61-’63, Cleveland ’64-’68, White Sox ’68.

KEOKUK PIRATES 1947 & 48 (Pittsburgh Pirates)
Gus Bell ‘47’48 23 games @ Keokuk.  ’50-’52 Pirates, ’53-61 Cincinnati, ’62 Mets, ’62-’64 Milwaukee Braves. Bell is the father of Buddy Bell and the grandfather of former Cardinal David Bell.