Kris Bryant ended a 24-game homerless drought, the longest of his career, and Ian Happ and Kyle Schwarber also went deep as the Chicago Cubs routed the St. Louis Cardinals 13-5 on Friday night.

Bryant drilled a 448-foot, two-run shot to left field off an ineffective Michael Wacha in the third inning for his first home run since May 14. The 2016 NL MVP capped a six-run fifth with an RBI single and drove in another run with a sacrifice fly in the seventh. His four RBIs were a season high.

Jon Lester ran his scoreless streak to 17 innings before giving up a solo home run to Marcell Ozuna in the fourth as the Cubs won for the first time in four tries at Busch Stadium this season. Lester (8-2) allowed two runs in six innings to earn his fourth straight win.

Lester helped himself at the plate, too, driving in a run on a bunt in the fourth and reaching on catcher Yadier Molina's throwing error that led to a second run as the Cubs extended their lead to 5-0.

Anthony Rizzo had three hits, was hit by a pitch and scored a run. Schwarber launched a three-run homer that traveled a projected 465 feet to straightaway center in the fifth, the third-longest homer by an opposing player in Busch Stadium III history.

Happ led off the third with a home run to right field. His first homer since May 22 snapped a 20-inning scoreless streak for the Cubs.

Wacha (8-2) allowed a career-high nine runs, eight earned, in a season-low four-plus innings. The three home runs he gave up tied a career high.

Matt Carpenter homered in the sixth and drove in two runs, but the Cardinals lost their third consecutive game.

TRAINER'S ROOM

Cubs: RHP Yu Darvish (right triceps tendinitis) threw a 35-pitch bullpen. He is scheduled to throw another one when the team returns home next week.

Cardinals: 1B Luke Voit was recalled from Double-A Springfield and RHP Matt Bowman (right hand finger blisters) was activated from the 10-day disabled list. 1B Jose Martinez was placed on the paternity list and RHP Daniel Poncedeleon was optioned to Triple-A Memphis.

UP NEXT

Cubs RHP Kyle Hendricks (4-6, 3.48 ERA) starts Saturday night against RHP Carlos Martinez (3-2, 2.96). Hendricks has dropped three straight decisions for the first time in his career. Martinez has walked 12 over 7 2/3 innings in two starts since returning from a lat strain.

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